个人资料
留学德国糖尿病研究中心（杜塞尔多夫）、法国核能署（巴黎）、美国宾夕法尼亚大学（费城）。主要研究方向包括：①营养、基因与代谢稳态；②动物肉质形成的分子基础及其调控；③细胞分化中的编程与重编程；④动物功能基因的转录调控和信号转导；⑤动物脂肪发育的分子机制及其调控。主持国家自然科学基金、广西自然科学基金重点项目、霍英东教育基金、欧洲糖尿病研究基金、教育部留学回国人员科研启动基金、教育部新教师基金等。在《Hepatology》、《Nucleic Acids Research》等国内外学术刊物上发表相关SCI收录论文20余篇。
工作经历
2013至今，广西大学，动物科学技术学院，教授。
2009－2013，华中农业大学，生命科学技术学院，教师。
现任广西大学动物科学技术学院副院长。
研究方向
①营养、基因与代谢稳态；
②动物肉质形成的分子基础及其调控；
③细胞分化中的编程与重编程；
④动物功能基因的转录调控和信号转导；
⑤动物脂肪发育的分子机制及其调控。
主要成就
开展研究工作以来，主持多项国家级、国际合作和省部级项目，发表相关论文二十余篇。围绕以上方向开展了较为系统的基础研究工作，取得了以下研究进展：
一、在动物整体水平上，发现抵抗素减少线粒体、增强脂肪异位沉积
二、在细胞水平上，证实脂肪细胞因子参与葡萄糖代谢、肌肉发育及炎症反应
三、在遗传水平上，开展猪脂肪代谢相关基因的克隆及转录调控研究
发表论文
1. Li H, Chen A, Shu L, Yu X, Gan L, ZhouL(通讯作者), Yang Z. Translocation of CIDEC in hepatocytes depends on fatty acids. . 2014, 19(11): 793-802. IF: 2.855
2. Lei Zhou(通讯作者), Xiaolan Yu, Qingjie Meng, Hongqiang Li, Congcong Niu, Yun Jiang, Yuxi Cai, Minghui Li, Qiang Li, Chaoqiang An, Le Shu, Ao Chen, Handong Su, Yin Tang, Shen Yin, Silja Raschke, Kristin Eckardt, Juergen Eckel, Zaiqing Yang. Resistin reduces mitochondria and induces hepatic steatosis in mice by the protein kinase C/protein kinase G/p65/PPAR gamma coactivator 1 alpha pathway. Hepatology. 2013, 57: 1384-1393. IF: 12.003
3. Lei Zhou, Gwenaelle Le Roux, Cecile Ducrot, Stephane Chedin, Jean Labarre, Michel Riva, Christophe Carles. Repression of class I transcription by cadmium is mediated by the Protein Phosphatase 2A. Nucleic Acids Res. 2013, 41: 6087–6097. IF: 8.278
4. Lei Zhou, Lijie Zhang, Qingjie Meng, Congcong Niu, Dan Jin, An Yu, Li gan, Zaiqing Yang. C/EBPa promotes transcription of the porcine perilipin5 gene. Mol Cell Endocrinnol. 2012; 364:28-35. IF: 4.192
5. Lei Zhou, Qingjie Meng, Tao Qian, Zaiqing Yang. Ginkgo biloba extract enhances glucose tolerance in hyperinsulinism-induced hepatic cells. J Nat Med. 2011; 65(1): 50-6. IF: 1.389
6. Lei Zhou, Henrike Sell, Kristin Eckardt, Zaiqing Yang, Jürgen Eckel. Conditioned medium obtained from in vitro differentiated adipocytes and resistin induce insulin resistance in human hepatocytes. FEBS letters. 2007; 581: 4303-4308. IF: 3.263
7. Lei Zhou, Yixing Li, Tao Nie, Shengqiu Feng, Huaping Chen, Zaiqing Yang. Clenbuterol inhibits SREBP-1c expression by activating CREB1. J BIOCHEM MOL BIOL. 2007; 40(4): 525-31. IF: 2.141
8. Lei Zhou, Tao Xia, Yixing Li, Xiaodong Chen, Yin Peng, Zaiqing Yang. Transcriptional Regulation of the Resistin Gene. Domest Anim Endocrinol. 2006; 30(2): 98-107. IF: 2.168
9. Lei Zhou, Yixing Li, Tao Xia, Shengqiu Feng, Xiaodong Chen, Zaiqing Yang. Resistin Overexpression Impaired Glucose Tolerance in Hepatocytes. Eur Cytokine Netw. 2006; 17(3): 189-95. IF: 1.216
10. 周磊，杨在清. 抗素的研究进展 .《中国兽医科学》 2006; 36(08): 684-686.
11. Yanling Wu, Qinqiang Long, Bin Feng, Xiaoyue Zhu, Zifeng Zheng, Sumin Gao, Mingju Gao, Li Gan, Lei Zhou, Zaiqing Yang. Molecular cloning and characterization of the anti-obesity gene adipose in pig. Gene. 2012; 509: 110-9. IF: 2.341
12. Chen Z, Gao X, Lei T, Chen X, Zhou L, Yu A, Lei P, Zhang R, Long H, Yang Z. Molecular characterization, expression and chromosome localization of porcine PNPLA3 and PNPLA4. Biotechnol Lett. 2011; 33(7): 1327-37. IF: 1.683
13. Zhang J, Lei T, Chen X, Peng Y, Long H, Zhou L, Huang J, Chen Z, Long Q, Yang Z. Resistin Up-Regulates COX-2 Expression via TAK1-IKK-NF-kappaB Signaling Pathway. Inflammation. 2010 Feb; 33(1): 25-33. IF: 1.777
14. Qi YM, Lei T, Zhou L, Chen XD, Long QQ, Long H, Jin D, Gan L, Yang ZQ. Genomic organization, alternative splicing and tissues expression of porcine CREB3L4 gene. Mol Biol Rep. 2009; 36(7): 1881-8. IF: 2.038
15. Y. H. Li, T. Lei, X. D. Chen, T. Xia, Q. Q. Long, J. Zhang, S. Q. Feng, Y. Peng, L. Zhou, Z. Q. Yang. Molecular cloning, chromosomeal location and expression pattern of porcine CIDEa and CIDEc. Mol Biol Rep. 2009 Mar; 36(3): 575-82. IF: 2.038
16. Qi M, Lei T, Zhou L, Chen XD, Long H, Long QQ, Zhang RR, Yang ZQ, Gan L. Cloning, Characterization, Chromosomal Mapping and Tissue Transcription Analysis of Porcine CREB2 and CREB3 Genes. Folia Biol(Praha). 2009; 55(4): 137-44. IF: 1.219
17. Yixing Li， Lei Zhou, Youguo Li, Dasong Chen, Xuejuan Tan, Lei Lei and Junchu Zhou. A Nodule-Specific Plant Cysteine Proteinase, AsNODF32, Is Involved in Nodule Senescence and Nitrogen Fixation Activity of the Green Manure Legume Astragalus sinicus. New Phytologist. 2008; 180: 185-192. IF: 5.178
18. Huaping Chen, Wenshu Yao, Dan Jin, Tao Xia, Xiaodong Chen, Ting Lei, Lei Zhou, Zaiqing Yang. Cloning, Expression Pattern, Chromosomal Localization, and Evolution Analysis of Porcine Gnaq, Gna11, and Gna14. Biochem Genet. 2008; 46(7-8): 398-405. IF: 0.75
19. Huaping Chen, Tao Xia, Lei Zhou, Xiaodong Chen, Li Gan, Wenshu Yao, Yin Peng, and Zaiqing Yang. Gene organization, alternate splicing and expression pattern of porcine visfatin gene. Domest Anim Endocrinol. 2007; 32: 235-45. IF: 2.528
20. HW Yang, T Xia, ZL Chen, SQ Feng, Y Peng, L Zhou, L Gan, and ZQ Yang. Cloning, chromosomal localization and expression patterns of porcine Kruppel-like factors 4, -5, -7 and the early growth response factor 2. Biotechnol Lett. 2007; 29(1): 157-63. IF: 1.222
21. Feng SQ, Chen XD, Xia T, Gan L, Qiu H, Dai MH, Zhou L, Peng Y, Yang ZQ. Cloning, chromosome mapping and expression characteristics of porcine ANGPTL3 and -4. Cytogenet Genome Res. 2006; 114(1): 44-9. IF: 1.839
