简介
2000年于曲阜师范大学获学士学位;2003年于南京大学获硕士学位;2013年于中国科学院大学(中科院西北高原生物研究所)获博士学位。2003年至今于曲阜师范大学化学与化工学院从事无机化学、无机化学双语课程、中级无机化学、高等无机化学、配位化学、无机化学实验、专业英语、文献检索课程教学。获曲阜师范大学教学项目1项,教学成果奖1项。先后从事量子化学(学士学位论文)、配位化学(硕士学位论文)、色谱质谱检测(博士学位论文)、荧光分子设计(当前研究兴趣)等领域研究。在Chemical Science, Biomaterials,Analytical Chemistry,Analyst,J Chromatography A,Food Chemistry,Talanta等重要期刊发表论文三十余篇;获批专利6项。多次担任期刊J Chromatography A的客座编辑及评委。主持国家自然基金面上项目1项、山东省自然基金青年基金1项、山东省肿瘤标志物检测技术重点实验室项目1项;完成校级科研项目2项。2014年获全国教育硕士专业学位优秀教学工作者(教指委【2014】06发文)。
研究方向:
• 多功能荧光分子探针设计合成及细胞内应用
• 有机分子药物传递及活体示踪
• 癌细胞荧光检测及药物筛选
• 基于荧光分子探针的生物标志物活体检测
欢迎在荧光传感生命有机分析、高效液相色谱及质谱、有机发光分子合成研究方面有理想、有追求的有志青年报考!
教学:
主讲课程:无机化学、无机化学实验、高等无机化学(本)、专业英语、文献检索、高等无机化学(研)、配位化学。
获奖:曾获曲师大化学院青年教师教学比赛中获得第二名,曲阜师范大学第四届青年教师授课大赛优秀奖;指导本科生毕业设计获校级优秀学士论文2篇(2007年、2013年),获省级优秀学士论文1篇;曲阜师范大学2016年度教学奖。
教学项目:
• 2007年:山东省基础学科专项资金建设项目-无机化学
• 2005年:曲阜师范大学《金属有机化学》双语教学研究
• 2009年:曲阜师范大学《化学学科双语教学研究》教学改革项目
• 2017年:曲阜师范大学《无机化学》双语教学项目
科研项目:
• 主持:国家自然基金面上项目1项、山东省自然基金青年项目1项、山东省肿瘤标志物检测技术重点实验室项目1项、完成曲师大校级科研项目2项;
• 参与:国家自然基金面上项目3项、国家自然基金青年项目4项、省自然基金青年项目3项。
代表性论文:
Kun Dou, Guang Chen*, Fabiao Yub, Yuxia Liua, Lingxin Chenb, Ziping Caoa, Tao Chenc, Yulin Lic and Jinmao You* Bright sensitive ratiometric fluorescent probe enabling endogenous FA imaging and mechanistic exploration of indirect oxidative damage of FA in various living systems.Chemical Science (IF=9.12, JCR一区) 2017, 2017, 8, 7851-7861.
G. Chen, Q. Fu, F. Yu, R. Ren, Y. Liu, Z. Cao, G. Li, X.-E. Zhao, L. Chen, H. Wang, Jinmao You. Wide-acidity-range pH fluorescence probes for evaluation of acidification in mitochondria and digestive tract mucosa. Anal. Chem.(IF=6.32, JCR一区)2017.
K. Dou, Q. Fu, G. Chen*, F. Yu, Y. Liu, Z. Cao, G. Li, X. Zhao, L. Xia, L. Chen, H. Wang, J. You, A novel dual-ratiometric-response fluorescent probe for SO2/ClO− detection in cells and in vivo and its application in exploring the dichotomous role of SO2 under the ClO− induced oxidative stress. Biomaterials.(IF=8.40, JCR一区)2017,133, 82-93.
Q. Fu, Z. Chen, X. Ma, G. Chen*, Y. Liu, Z. Cao, F. Qu, D. Yang, X. Zhao, Z. Sun, G. Li, S. Zhang, F. Qu, R. Kong, H. Wang, J. You, Simultaneous absorbance-ratiometric, fluorimetric, and colorimetric analysis and biological imaging of α-ketoglutaric acid based on a special sensing mechanism. Sensor Actuat B-chem(IF=5.40, JCR一区)2017,241, 1035-1042.
Q. Fu, G. Chen*, Y. Liu, Z. Cao, X. Zhao, G. Li, F. Yu, L. Chen, H. Wang, J. You, In situ quantification and evaluation of ClO−/H2S homeostasis in inflammatory gastric tissue by applying a rationally designed dual-response fluorescence probe featuring a novel H+-activated mechanism. Analyst(IF=3.89, JCR二区)2017,142, 1619-1627.
X. Li, G. Chen*, J. Liu, Y. Liu, X. Zhao, Z. Cao, L. Xia, G. Li, Z. Sun, S. Zhang, H. Wang, J. You, A rapid, accurate and sensitive method with the new stable isotopic tags based on microwave-assisted dispersive liquid-liquid microextraction and its application to the determination of hydroxyl UV filters in environmental water samples. Talanta(IF=4.16, JCR二区).2017, 167, 242-252.
M Liu, G Chen*, H Guo, B Fan, J Liu, Jinmao You. "Accurate Analysis and Evaluation of Acidic Plant Growth Regulators in Transgenic and Nontransgenic Edible Oils with Facile Microwave-Assisted Extraction." J. Agric. Food Chem.,(IF=3.15, JCR一区)2015, 63 (36), pp 8058–8067.
J. Liu, M. Liu, X. Li, X. Lu, G. Chen*, Z. Sun, G. Li, X. Zhao, S. Zhang, C. Song, Jinmao You. Development of ultrasonic-assisted closed in-syringe extraction and derivatization for the determination of labile abietic acid and dehydroabietic acid in cosmetics. J Chromatogr A(IF=4.02, JCR二区)2014, 1371, 20-29.
G. Chen,J. Liu, M. Liu, G. Li, Z. Sun, S. Zhang, C. Song, H. Wang, Y. Suo, J. You, Sensitive, accurate and rapid detection of trace aliphatic amines in environmental samples with ultrasonic-assisted derivatization microextraction using a new fluorescent reagent for high performance liquid chromatography J Chromatogr A(IF=4.02, JCR二区)2014, 1352, 8-19.
Chen, G., J. Li, Jinmao You et al. (2013). "Rapid and sensitive ultrasonic-assisted derivatization microextraction (UDME) technique for Bitter taste-Free amino acids (FAA) study by HPLC-FLD." Food Chemistry.(IF=4.53, JCR二区)2014,143, 97-105.
Guang Chen, Jun Li Shijuan Zhang Cuihua Song Guoliang Li Zhiwei Sun Yourui Suo, Jinmao You*, A sensitive and efficient method to systematically detect two biophenols in medicinal herb, herbal products and rat plasma based on thorough study of derivatization and its convenient application to pharmacokinetics with semi-automated device, Journal of Chromatography A(IF=4.02, JCR二区)Volume 1249, 3,190-200,2012.
Guang Chen*, Jun Li Cuihua Song Yourui Suo Jinmao You*,A sensitive and efficient method for simultaneous trace detection and identification of triterpene acids and its application to pharmacokinetic study, Talanta(IF=4.16, JCR二区),98, 30, 101–111, 2012.
其他:
04年9月-05年12月:04级化工班辅导员
06年1月-10年3月:研究生教学秘书、本科生教学秘书
2010年3月-至今:院办公室主任、研究生教学秘书