个人简介
入选“万人计划青年拔尖人才计划”、中国科学院首批“卓越青年科学家”;曾获“日本实验动物学会国际奖”、“中国干细胞学会青年研究员奖”、“中国科学院杰出科技成就(集体奖)”、“盖茨基金会–青年科学家”等奖励;获国家重大科学研究计划、基金委优秀青年基金等项目支持。
研究领域
干细胞基因组稳定性和倍性调控的机制与方法,以及基因组修饰技术的开发与应用。
社会任职
2014.1- 中国动物学会生殖生物学分会理事
2014.1- 中国科学院青年创新促进会 会员
2013.1- 中国遗传学会青年委员会 委员
2013.1- 国际干细胞研究协会(ISSCR)会员
承担科研项目情况
国家重大基础研究计划项目,中国科学院科研装备研制项目,国家自然科学基金委员会优秀青年基金项目、面上项目,中国科学院科研装备研制项目。
代表论著
(# 同等贡献作者; * 通讯作者)
Li X#, Cui XL#, Wang JQ #, Wang YK, Li YF, Wang LY, Wan HF, Li TD, Feng GH, Shuai L, Li ZK, Gu Q, Hao J, Wang L, Zhao XY, Liu ZH, Wang XJ, Li W*, Zhou Q*. Generation and Application of Mouse-Rat Allodiploid Embryonic Stem Cells. Cell 164(1–2) (2016): 279–292.
Li ZK#, Wan HF#, Feng GH#, Wang LY#, He ZQ, Wang YK, Wang XJ, Li W*, Zhou Q*, Hu BY*. Birth of fertile bimaternal offspring following intracytoplasmic injection of parthenogenetic haploid embryonic stem cells. Cell Research 26 (2016):135–138.
Li W#, Li X#, Li TD#, Jiang MG#, Wan HF, Luo GZ, Feng CJ, Cui XL, Teng F, Yuan Y, Zhou Q, Gu Q, Shuai L, Sha JH, Xiao YM, Wang L, Liu ZH, Wang XJ, Zhao XY, Zhou Q*. Genetic modification and screening in the rat using haploid embryonic stem cells. Cell Stem Cell 14(3) (2014):404-414.
Li W, Teng F, Li TD, Zhou Q*. Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems. Nature Biotechnology 31(2013): 684–686.
Li W#, Guo XJ#, Teng F, Hou XJ, Lv Z, Zhou SY, Bi Y, Wan HF, Feng CJ, Yuan Y, Zhao XY, Wang L, Sha JH*, Zhou Q*. Tex101 is essential for male fertility by affecting sperm migration into the oviduct in mice. Journal of Molecular Cell Biology 5 (5) (2013): 345-347.
Li W#, Shuai L#, Wan HF#, Dong MZ#, Wang M, Sang LS, Feng CJ, Luo GZ, Li TD, Li X, Wang LB, Zheng QY, Sheng C, Wu HJ, Liu ZH, Liu L, Wang L, Wang XJ, Zhao XY*, Zhou Q*. Androgenetic haploid embryonic stem cells produce live transgenic mice. Nature 490(7420) (2012):407-411.
Li W#, Zhao XY#, Wan HF, Zhang Y, Liu L, Lv Z, Wang XJ, Wang L*, Zhou Q*. iPS cells generated without c-Myc have active Dlk1-Dio3 region and are capable of producing full-term mice through tetraploid complementation. Cell Research 21(3) (2011):550-553.
Zhao XY#, Li W#, Lv Z#, Liu L, Tong M, Hai T, Hao J, Guo CL, Ma QW, Wang L, Zeng FY*, Zhou Q*. iPS cells produce viable mice through tetraploid complementation. Nature 461(7260)(2009):86-90.